Short Communication Structural polymorphism of the mannose-binding lectin 2 (MBL2) gene in HCV-infected patients with a serological marker for thyroid autoimmunity

F. M. Melo; L. R.S. Vasconcelos; B. S. Silva; P. Moura; M. S.M. Cavalcanti; L. M.M.B. Pereira; H. R. Lacerda

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Short Communication Structural polymorphism of the mannose-binding lectin 2 (MBL2) gene in HCV-infected patients with a serological marker for thyroid autoimmunity

International Journal of Immunogenetics (2009) 36(6) 377-381

DOI: 10.1111/j.1744-313X.2009.00871.x

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Abstract

We studied the association of the mannose-binding lectin-2 (MBL2) polymorphism with anti-thyroid antibodies (ATA) in hepatitis C virus (HCV)-infected Brazilian patients (n = 162) and 124 healthy volunteers screened for ATA. Our results showed that patients with ATA had higher frequency of genotype 00 than controls. MBL may play a role as disease modifier in HCV infection. © 2009 Blackwell Fublishing Ltd.

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Melo, F. M., Vasconcelos, L. R. S., Silva, B. S., Moura, P., Cavalcanti, M. S. M., Pereira, L. M. M. B., & Lacerda, H. R. (2009). Short Communication Structural polymorphism of the mannose-binding lectin 2 (MBL2) gene in HCV-infected patients with a serological marker for thyroid autoimmunity. International Journal of Immunogenetics, 36(6), 377–381. https://doi.org/10.1111/j.1744-313X.2009.00871.x

Short Communication Structural polymorphism of the mannose-binding lectin 2 (MBL2) gene in HCV-infected patients with a serological marker for thyroid autoimmunity

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