Single-laser light source for CARS microscopy based on soliton self-frequency shift in a microstructured fiber

Abstract

A femtosecond light source comprising two highintensity beams at different wavelengths is applied to coherent anti-Stokes Raman scattering microscopy. One wavelength is supplied by a Titanium: Sapphire oscillator, while the other is derived from that via soliton-self-frequency shift in a microstructured fiber. Clear CARS images are acquired with the frequency difference adjusted to resonances of polystyrene and lipids. © Springer-Verlag 2010.