Chronic Obstructive Pulmonary Disease (Copd)

Abstract

Chronic obstructive pulmonary disease (COPD), characterized by airway remodeling, infiltration of inflammatory cells, is the most common chronic lung disease in the world. The imbalance between protease and antiprotease, as well as oxidative stress, is considered to be common mechanism of the pathology of COPD. As of now, different biological markers have been used as indicators of the different aspects of COPD pathology. Among them, some glycosyltransferases, glycoproteins, and glycans are reported to play important roles in COPD progression. This review is provided to address the current status of the disease with emphasis on recent progress on addressing the above key factors.