Ontologies are powerful and popular tools to encode data in a structured format and manage knowledge. A large variety of existing ontologies offer users access to biomedical knowledge. This chapter contains a short theoretical background of ontologies and introduces two notable examples: The Gene Ontology and the ontology for Biological Pathways Exchange. For both ontologies a short overview and working bioinformatic applications, i.e., Gene Ontology enrichment analyses and pathway data visualization, are provided.
CITATION STYLE
Kramer, F., & Beißbarth, T. (2017). Working with ontologies. In Methods in Molecular Biology (Vol. 1525, pp. 123–135). Humana Press Inc. https://doi.org/10.1007/978-1-4939-6622-6_6
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