The natural history of psoriatic arthritis

Abstract

Psoriatic arthritis is an infl ammatory arthritis that usually appears after, or synchronously with, the onset of psoriasis. The disease may manifest in a variety of phenotypes, follows a relapsing and remitting course, with articular damage and functional impairment accumulating over time. Delay to diagnosis results on worse clinical, functional and radiographic outcome. The natural history of disease in the modern era of novel biological treatments and tighter disease control has yet to be determined.