Following intracerebral hemorrhage (ICH) there is a sequential response involving activation of the coagulation cascade/platelet plug formation, vascular repair, upregulation of endogenous defense mechanisms and clot resolution. How these responses are coordinated and modified by different hematoma sizes has received little attention. This paper reviews evidence that thrombin can modulate and may coordinate the components of the endogenous response. This has potential consequences for treatment of ICH with a number of modalities. © 2011 Springer-Verlag/Wien.
CITATION STYLE
Keep, R. F., Xi, G., Hua, Y., & Xiang, J. (2011). Clot formation, vascular repair and hematoma resolution after ICH, a coordinating role for thrombin? In Acta Neurochirurgica, Supplementum (pp. 71–75). Springer-Verlag Wien. https://doi.org/10.1007/978-3-7091-0693-8_12
Mendeley helps you to discover research relevant for your work.