Methylation of DNA repair genes and the efficacy of DNA targeted anticancer treatment

  • Julsing J
  • Peters G
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Abstract

AbstractCancer is considered both a genetic and epigenetic disease. The best studied epigenetic mechanism in carcinogenesis is DNA methylation, a mechanism which inactivates tumor suppressor genes by methylating their promoters. A

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Julsing, J. R., & Peters, G. J. (2014). Methylation of DNA repair genes and the efficacy of DNA targeted anticancer treatment. Oncology Discovery, 2(1), 3. https://doi.org/10.7243/2052-6199-2-3

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