After attachment to specific receptors on the surfaces of target cells, hepatitis C virus (HCV) particles are thought to be internalized to endosomes, where low pH induces fusion between the viral and cellular membranes, delivering the HCV genome into the cytoplasm. Here, we describe methods to study the early events in HCV infection; the interactions with cellular receptors and the mechanism of entry.
CITATION STYLE
Flint, M., & Tscherne, D. M. (2009). Cellular receptors and HCV entry. Methods in Molecular Biology (Clifton, N.J.), 510, 265–277. https://doi.org/10.1007/978-1-59745-394-3_20
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