The Golgi apparatus: State of the art 110 years after Camillo Golgi's discovery

Abstract

For over 110 years The Golgi complex has been at the center of interest and scientific debates. It constitutes a main crossroads in secretory and endocytic traffic. However, despite thousands of details known about architecture, organization, and transport mechanisms across the Golgi stacks of cisternae, and potentially due to this plethora of information, it is difficult to find explanations, how the complex system works. This book summarizes all new data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy collecting the full range of expertise, different points of view and different approaches. The book is devoted to molecular modes of the function of the Golgi apparatus as a whole, taking into account all experimental data even if they contradict existing models of Golgi function. The aim of the book is to make the functional organization of the Golgi apparatus more understandable by keeping it as simple as possible but also as full as possible.