Rifampin‐induced acute kidney injury and hemolysis: A case report and literature review of a rare condition

Abstract

Rifampicin is a bactericidal drug used in various infectious diseases, including tuberculosis (TB). Nephrotoxicity is a rare side effect of intermittent Rifampin use and even less commonly continued use. We report a case of Rifampin‐induced acute tubular necrosis and hemolysis in a patient with latent TB with a relevant literature review.Acute kidney injury with hemolysis due to Rifampin (intermittent or continuous use) is rare and mainly presents as acute tubular necrosis or acute interstitial nephritis. The mechanism of injury is probably autoimmune‐mediated, with a good recovery.