Neuromarkers

Abstract

Traumatic brain injury (TBI) is a significant cause of mortality and morbidity in adults and a leading cause of death in childhood. The diagnostic process includes clinical examination and in more severe cases neuroimaging, such as computed tomography of the head (CT) or magnetic resonance imaging (MRI). Biochemical markers are constantly being used as diagnostic tools for injuries in specific organs, such as troponin for myocardial infarction, creatinine for renal dysfunction and pancreas amylase and lipase for acute pancreatitis. A biomarker detectable in serum, and easily analysed, would be preferable as a complement to clinical assessment after TBI.