Spectroscopic study on the interaction of Al3+ with flavonoids and BSA

Abstract

The interaction of Chinese herbal medicine component flavonoids (morin and rutin) with trivalent aluminium ion and the complex of aluminium ion and Bovine Serum Albumin in Hank's artificial simulate body fluid was studied using UV-Vis absorption spectra. The result showed that morin and rutin could conjugate with Al3+ in Hank's artificial simulate body fluid. It was found that morin and rutin could competed with the complex of aluminium ion and Bovine Serum Albumin for aluminium ion. The mechanism of flavonoids and Bovine Serum Albumin compete aluminium ion was discussed, and the constant of rutin complex with aluminium ion was calculated. © 2006 SIOC, CAS, & Wiley-VCH Verlag GmbH & Co. KGaA.