Abstract
Total liquid ventilation (TLV) is an innovative experimental method of mechanical ventilation in which lungs are totally filled with a breathable perfluorochemical liquid (PFC). The main objective is to develop a method to estimate the alveolar pressure from a pressure mouth measurement during pause in liquid ventilation. Experimental results show that the measured mouth pressure is disturbed by disturbances (damped oscillations due to fluid-structure tube resonances and cardiogenic oscillation). Numerical analysis of PY allow to obtain a fractional-order model of α= 0.7 for the alveolar pressure.
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Vandamme, J., Nadeau, M., Mousseau, J., Praud, J. P., & Micheau, P. (2019). Model of the Mouth Pressure Signal During Pauses in Total Liquid Ventilation. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 11466 LNBI, pp. 573–581). Springer Verlag. https://doi.org/10.1007/978-3-030-17935-9_51
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