Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection

Man-Fung Yuen; Seng-Gee Lim; Robert Plesniak; Keiji Tsuji; Harry L.A. Janssen; Cristina Pojoga; Adrian Gadano; Corneliu P. Popescu; Tatyana Stepanova; Tarik Asselah; Gheorghe Diaconescu; Hyung Joon Yim; Jeong Heo; Ewa Janczewska; Alexander Wong; Nevin Idriz; Michio Imamura; Giuliano Rizzardini; Koichi Takaguchi; Pietro Andreone; Manuela Arbune; Jinlin Hou; Sung Jae Park; Andrei Vata; Jennifer Cremer; Robert Elston; Tamara Lukić; Geoff Quinn; Lauren Maynard; Stuart Kendrick; Helene Plein; Fiona Campbell; Melanie Paff; Dickens Theodore

Journal ArticleOPEN ACCESS

Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection

Yuen M
Lim S
Plesniak R
et al.

New England Journal of Medicine (2022) 387(21) 1957-1968

DOI: 10.1056/nejmoa2210027

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Abstract

Abstract Background Bepirovirsen is an antisense oligonucleotide that targets all hepatitis B virus (HBV) messenger RNAs and acts to decrease levels of viral proteins. Methods We conducted a phase ...

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APA

Yuen, M.-F., Lim, S.-G., Plesniak, R., Tsuji, K., Janssen, H. L. A., Pojoga, C., … Theodore, D. (2022). Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection. New England Journal of Medicine, 387(21), 1957–1968. https://doi.org/10.1056/nejmoa2210027

Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection

Abstract

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