Pioneers in the early years of cytochrome P450 research

Abstract

Since the discovery of “cytochrome P450” in 1962, many biochemists have intensively studied various problems of this unique hemoprotein and contributed to the elucidation of its molecular properties and physiological functions. This review chapter describes the important contributions by the pioneer scientists in the early years of research on P450. A few important events that preceded and were pertinent to the discovery of P450 are also described.