MicroRNAs, gene's regulator in prostate cancer

Abstract

Since the discovery of microRNAs (miRNAS) in 1993, findings in gene regulation have increased in the biological scenery. miRNAs have shown an important role in the modulation of a wide collection of physiological and pathological processes, starting on embryonic evolution with carcinomas development. Nowadays, the high availability of gene expression data and the development of computational approaches that predicts miRNA targets are continuously increasing the knowledge about miRNA functions, as well as the sources and consequences of miRNA deregulation within a wide interaction network. In this chapter, knowledge of miRNA expression and its function on prostate cancer is presented.