Synthesis and biological activity of N-substituted spiro[benzoxazepinepiperidine] Aβ-peptide production inhibitors

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Abstract

Synthesis and biological evaluation of an spiro[benzoxazepine-piperidine] class of Aβ-peptide production inhibitors for treatment of Alzheimer's disease are described.

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Laras, Y., Pietrancosta, N., Tomita, T., Iwatsubo, T., & Kraus, J. L. (2008). Synthesis and biological activity of N-substituted spiro[benzoxazepinepiperidine] Aβ-peptide production inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry, 23(6), 996–1001. https://doi.org/10.1080/14756360701832706

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