Objectives: Central giant-cell granuloma (CGCG) is a benign, non-odontogenic lesion of uncertain origin and well-known epidemiologic, clinical and radiologic characteristics. The aim of this study was to compile, describe and evaluate the authors' experience with the surgical treatment of CGCG and its follow-up, with special emphasis on clinical and radiologic data, complications and recurrences. The scientific literature was reviewed. Material and methods: A retrospective study was made of 10 cases treated surgically at our center between 1998 and 2008. The mean age of patients was 35 years. The clinical and radiological characteristics of each case were described, as well as the best surgical option and the evaluation, complications, and recurrences. Results: All 10 cases, 4 of which exhibited aggressive clinical and radiologic behavior, were treated surgically. The treatment of choice was excision and curettage to healthy bone in 60% and resection with a surgical margin in the rest. Mean follow-up was 6.7 years and the recurrence rate was 1%. Conclusion: The authors share the opinion of other authors that surgery is currently the treatment of choice. Adequate diagnosis and clear differentiation between aggressive and non-aggressive lesions is important in deciding how radical the intervention should be. © 2011 SECOM.
Fernández Ferro, M., Fernández Sanromán, J., Costas López, A., Sandoval Gutiérrez, J., & López de Sánchez, A. (2011). Tratamiento quirúrgico del granuloma central de células gigantes: Estudio y seguimiento de 10 casos. Revisión de la literatura. Revista Espanola de Cirugia Oral y Maxilofacial, 33(1), 1–8. https://doi.org/10.1016/S1130-0558(11)70001-6