Genetic Diseases of Oral Mucosa

Abstract

A number of genetic or systemic diseases have characteristic manifestations of the oral mucosa. In the majority of these disorders, the oral lesions follow the onset of the skin or systemic disease and in some they appear simultaneously; however, there are few genetic diseases where the oral manifestations represent the first clinical sign of the generalized disease. Although the oral manifestation only rarely is necessary for the diagnosis, it sometimes represents the key point without which the diagnosis would be very difficult.