A mathematical model based on kinetic data taken from the literature is presented for the pentose phosphate pathway in fasted rat liver steady-state. Since the oxidative and non oxidative pentose phosphate pathway can act independently, the complete (oxidative + non oxidative) and the non oxidative pentose pathway were simulated. Sensitivity analyses are reported which show that the fluxes are mainly regulated by D-glucose-6-phosphate dehydrogenase (for the oxidative pathway) and by transketolase (for the non oxidative pathway). The most influent metabolites were the group ATP, ADP, P1 and the group NADPH, NADP+ (for the non oxidative pathway). © 1995 Kluwer Academic Publishers.
CITATION STYLE
Sabate, L., Franco, R., Canela, E. I., Centelles, J. J., & Cascante, M. (1995). A model of the pentose phosphate pathway in rat liver cells. Molecular and Cellular Biochemistry, 142(1), 9–17. https://doi.org/10.1007/BF00928908
Mendeley helps you to discover research relevant for your work.