A trimethoxyellagic acid glucuronide from Conocarpus erectus leaves: Isolation, characterization and assay of antioxidant capacity

Abstract

The new trimethoxy-ellagic glycoside, 3,3′,4′-tri-O- methylellagic acid 4-O-β-glucupyranuronide and twelve known phenolics were isolated from the leaves of Conocarpus erectus L. (Combretaceae). Structures of all compounds were determined on the basis of spectroscopic methods and chemical degradation. The new compound, together with four of the isolated known constituents and the plant extract itself, showed potent inhibitory effect against reactive oxygen species attack on salicylic acid in a dose-dependent manner adopting xanthine/hypoxanthine oxidase assay. © 2010 Informa UK Ltd.