Abstract
Two heteronuclear proton-carbon NMR experiments are applied to the DNA-octamer d(TTGGCCAA)2 with carbon in natural abundance. They lead to a complete assignment of the carbon resonances of the sugars and bases. In addition, several heteronuclear coupling constants, proton-carbon as well as proton-phosphorous and phosphorous-carbon, were determined. The information can be obtained in a resonable measuring time and offers valuable information for a detailed picture of DNA structure. © 1992 Oxford University Press.
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CITATION STYLE
Schmieder, P., Ippel, J. H., Van Den Elst, H., Van Der Marel, G. A., van Boom, J. H., Altona, C., & Kessler, H. (1992). Heteronuclear NMR of DNA with the heteronucleus in natural abundance: Facilitated assignment and extraction of coupling constants. Nucleic Acids Research, 20(18), 4747–4751. https://doi.org/10.1093/nar/20.18.4747
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