We present a method to capture mesenchymal stromal cells (MSCs) by adhesion to extracellular matrix (ECM) molecules under flow conditions. The technique simulates a physiological system and exploits the natural biological interactions of cells, through integrin receptors, with their ECM. The system offers an insight into how MSCs could be targeted/localized to the site of interest (graft) following intravenous injection.
CITATION STYLE
Massam-Wu, T., Cain, S. A., & Kielty, C. M. (2018). Extracellular matrix molecule-based capture of mesenchymal stromal cells under flow. In Methods in Molecular Biology (Vol. 1722, pp. 249–260). Humana Press Inc. https://doi.org/10.1007/978-1-4939-7553-2_16
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