The Properties of Poly (Acrylic Acid) Modified with NPhenylbenzothioamide as Potential Drug Carriers

Abstract

Poly(acrylic acid) and N-phenylbenzothioamide have been synthesized under laboratory conditions. The purity of products has been checked by FTIR and NMR spectroscopy. The obtained N-phenylbenzothioamide has been used for modification of poly(acrylic acid) properties. The prepared blend of PAA contained small amout of dopant (1-5 wt %). Thermal and photochemical stability of obtained specimens were investigated using UV-Vis spectroscopy and thermogravimetric analysis. Crosslinking yield was estimated by extraction of insoluble gel formed. It was found that N-phenylbenzothioamide stabilizes poly(acrylic acid) during UV-irradiation which is explained by efficient crosslinking reaction.