The use of genetically isolated populations can empower next-generation association studies. In this review, we discuss the advantages of this approach and review study design and analytical considerations of genetic association studies focusing on isolates.We cite successful examples of using population isolates in association studies and outline potential ways forward.
CITATION STYLE
Hatzikotoulas, K., Gilly, A., & Zeggini, E. (2014). Using population isolates in genetic association studies. Briefings in Functional Genomics, 13(5), 371–377. https://doi.org/10.1093/bfgp/elu022
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