Dark-field hyperspectral system for monitoring the nanoparticles interaction with the cells

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Abstract

Nanomaterials are commonly used in biomedical research, mostly in cancer diagnosis and therapy. In this study, we used dark-field hyperspectral systems to investigate nanomaterials for the biological interaction of the opsonized or pegylated nanomaterials. Gold nanoparticles have good biocompatibility and exhibit strong light scattering behavior under the dark- field microscope. Those properties make it feasible to study the interaction between the surface functionalized nanomaterials and cellular micro-environments multidimensionally.

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Wang, C. W., Huang, W. C., Huang, Z. Y., Lin, Y. T., Chang, W. H., & Lin, C. A. J. (2015). Dark-field hyperspectral system for monitoring the nanoparticles interaction with the cells. In IFMBE Proceedings (Vol. 47, pp. 18–20). Springer Verlag. https://doi.org/10.1007/978-3-319-12262-5_6

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