Convenient Approach to Access Octa-Glycosylated Porphyrins via “Click Chemistry”

  • Okada M
  • Kishibe Y
  • Ide K
  • et al.
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Abstract

Easy, quantitative, and one-pot introduction of eight β -lactoside-modules onto a porphyrin-core was achieved through Cu + -catalyzed chemoselective coupling (click chemistry) between a porphyrin carrying eight alkyne-terminals and β -lactosyl azides. The obtained porphyrin-based glycocluster shows not only good water-solubility but also strong/specific lectin-affinity.

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Okada, M., Kishibe, Y., Ide, K., Takahashi, T., & Hasegawa, T. (2009). Convenient Approach to Access Octa-Glycosylated Porphyrins via “Click Chemistry.” International Journal of Carbohydrate Chemistry, 2009, 1–9. https://doi.org/10.1155/2009/305276

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