Tranexamic acid for major spine surgery

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Abstract

A 55-year old man presents for elective L3-L5 lumbar laminectomy with decompression. His medical history consists of hypertension, well controlled with amlodipine. In addition, he suffers from chronic back pain due to lumbar radiculopathy and spinal stenosis. His laboratory work, including electrolytes, complete blood count, and coagulation factors, is normal. The surgeon is asking you to give the patient tranexamic acid (TXA) to reduce intraoperative bleeding. You wonder whether the benefits of TXA outweigh its downsides.

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Pisklakov, S. (2016). Tranexamic acid for major spine surgery. In You’re Wrong, I’m Right: Dueling Authors Reexamine Classic Teachings in Anesthesia (pp. 193–195). Springer International Publishing. https://doi.org/10.1007/978-3-319-43169-7_56

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