Abstract
Mitochondrial toxicity has been recently suggested to be the underlying mechanism of long-term linezolid-associated toxicity in patients with 16S rRNA genetic polymorphisms. Here, we report for the first time two cases of lactic acidosis due to long-term linezolid exposure in liver transplant recipients who presented an A2706G mitochondrial DNA polymorphism. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
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CITATION STYLE
Del Pozo, J. L., Fernández-Ros, N., Sáez, E., Herrero, J. I., Yuste, J. R., & Banales, J. M. (2014). Linezolid-induced lactic acidosis in two liver transplant patients with the mitochondrial DNA A2706G polymorphism. Antimicrobial Agents and Chemotherapy, 58(7), 4227–4229. https://doi.org/10.1128/AAC.02856-14
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