We have developed a novel method to evaluate the potential profile of a molecular motor at each chemical state from only the probe's trajectory and applied it to a rotary molecular motor F 1-ATPase. By using this method, we could also obtain the information regarding the mechanochemical coupling and energetics. We demonstrate that the position-dependent transition of the chemical states is the key feature for the highly efficient free-energy transduction by F 1-ATPase. © 2012 Europhysics Letters Association.
CITATION STYLE
Toyabe, S., Ueno, H., & Muneyuki, E. (2012). Recovery of state-specific potential of molecular motor from single-molecule trajectory. EPL, 97(4). https://doi.org/10.1209/0295-5075/97/40004
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