Thiamine Deficiency and Benfotiamine Therapy in Brain Diseases

Abstract

Thiamine is hydrosoluble molecule from B vitamins family vitamin that is crucial for the metabolism of glucose and is essential for the normal growth and development of the organism, as well as for the normal function of body systems such as digestive, cardiovascular and nervous system, both central (CNS) and peripheral (PNS), and also stimulates the brain and improves the psycho-emotional state. Hypovitaminosis B1 is more common than it is thought, primarily due to the discrepancy in high intake of pure calories and the low intake of vitamins. The most frequent deficiencies of thiamine are Wernicke’s encephalopathy, Korsakoff’s psychosis, beriberi, Alzheimer’s disease, but many more cases are those of marginal deficit of thiamine.