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Enabling migration by moderation: YAP/TAZ are essential for persistent migration

Journal of Cell Biology
DOI: 10.1083/JCB.201902035
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Abstract

Persistent cell migration plays a crucial role in physiological processes, but its underlying mechanisms of regulation remain unclear. Mason et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201806065) show that YAP/TAZ limit cytoskeletal tension, which is essential for persistent (but not initiation of) cell migration. Potential implications of this study range from embryonic development to metastasis.

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Nair, P. R., & Wirtz, D. (2019, April 1). Enabling migration by moderation: YAP/TAZ are essential for persistent migration. Journal of Cell Biology. Rockefeller University Press. https://doi.org/10.1083/JCB.201902035

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