Mass Spectrometry Data Analysis in Proteomics. Methods in Molecular Biology.

Abstract

This book has been prepared to start outwith a basic introduction to mass spectrometry-based proteomics. The introductory chapter is followed by chapters written by experts in specific subdomains of MS-based proteomics. The experts present their view on specific MS-based methods or data analysis strategies in proteomics. The book is written with the purpose of covering specific topics in detail rather than glossing over the topic. Detailed discussion is made possible since Springer allowed no page restriction on the experts’ chapters. This is the second edition of the book, and, in the 6 years since the publishing of the first edition, the instrumentation and methods have been considerably improved. My personal experience as editor has also been enhanced. I promise the reader that much effort and time have been devoted to making the book up-to-date, and, in fact, every single chapter is either new or has been completely rewritten. I have no doubt that this book is useful for everyone working in proteomics. I have to thank the many invited authors for their on-time delivery and detailed chapters. The authors have provided original manuscripts and even novel concepts in some cases. The book covers data analysis topics relevant for quantitative proteomics, posttranslational modification, HX-MS, glycomics, and data exchange standards.