Research Study 2

Abstract

Alopecia areata is a relatively common dermatitis with 0.1–0.2% prevalence, manifested by sudden and non-scarring hair loss. Multiple etiologies have been proposed for this disease. Among which the theory of its autoimmune nature and genetic/environmental factors has been highlighted. Currently there is no certain cure for alopecia areata. Numerous treatments have been proposed, but all of them are partially effective and none of them have led to complete improvement. One of the most popular treatments is the application of local allergens which by inducing contact allergic dermatitis stimulates hair growth. One of these allergens is diphencyprone which induces an allergic response in 98–99% of patients, and its effectiveness was reported between 4% and 85%. However, for severe cases it is more effective than other proposed methods.