B cells and humoral immune response decline in elderly individuals. Age-related changes in B cell commitment and development include decline in frequency of precursors. Recent studies showed a remarkable decline in pre-B cell numbers in aged mice without decrease in the number of mature B cells. This chapter briefly reviewed B cells changes during ageing.
CITATION STYLE
Nicknam, M. H., & Rezaiemanesh, A. (2014). Effects of aging on B cells. In Immunology of Aging (pp. 207–209). Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/978-3-642-39495-9_14
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