Recalcification of carious lesion with AIDS of calcium oxide nanoparticles

Abstract

Application of CaO nanoparticles has been stated to have a promising effect in the increasing of the resistance of mineralized tissue against cryogenic challenge. This project aimed to investigate the recalcifying efficacy CaO nanoparticles applied to the natural lesion. Thirty enamel samples were prepared from premolar teeth. They were divided into two main groups of three subgroups in each (Sub-G1, Sub-G2, and Sub-G3), one group from the affected area and another from the adjacent sound area. The samples in Sub-G1 were coated with the bonding agent, in Sub-G2 were coated with CaO nanoparticles loaded bonding agent, and Su-G3 with no coating (control). After storage in artificial saliva, the mineral contents were quantified with aids of scanning electron microscope fitted with energy dispersive spectroscopy (SEM-EDX). The statistical analysis displayed an increase in the Ca surface contents of carious and sound samples in Sub-G2. This indicates that coating the enamel with CaO nanoparticles loaded bonding agent could enhance the remineralization of naturally demineralized hard tissue and provide protection for the sound tissue.