P05.15 Surgically treated meningiomas at Dr. Cipto Mangunkusumo General Hospital: clinicopathological aspects

Abstract

BACKGROUND: Intracranial meningiomas are a common type of primary brain tumors. We would like to examine the profile of intracranial meningiomas at our institution. MATERIAL AND METHODS: We analysed the incidence and clinical, radiological, pathological features of meningiomas at Dr. Cipto Mangunkusumo General Hospital retrospectively between January 2012 and December 2017. The records of all surgically treated meningiomas were analysed from the medical record unit. RESULTS: We found 431 intracranial meningiomas were surgically resected at our institution. The patients had a median age of 45 years and were predominantly female (383 female and 48 male). WHO grade I meningiomas accounted for approximately 74 % of the intracranial meningiomas (316 of total 431 patients). WHO grade II and grade III meningiomas were found in 99 (22.9%) and 13 patients (3.1%) respectively. of the histological subtypes, the most common are meningothelial in 71 patients (16.5%), mixed meningothelial and microcystic in 53 patients (12.3%) and mixed meningothelial and transitional in 41 patients (9.5%), whereas the uncommon subtypes such as atypical, angiomatous, anaplastic, clear cell, secretoric, chordoid, rhabdoid were found in 35 patients (8.1%). The most common site of meningioma is sphenoorbita region (223 patients; 51.9%.), followed by convexity (60 patients; 13.9%), and sphenoid wing (30 patients; 7.0%). Proptosis is the most common clinical presentation (176 patients; 40.8%), followed by decrease of visual acquity (75 patients; 17.4%) and headache (46 patients; 10.8%). CONCLUSION: This study showed intracranial meningiomas are a female preponderance among our patients. Proptosis is the most common clinical presentation, the sphenoorbita region as the most common site, whereas WHO grade I and meningothelial subtypes as the most common pathological finding.