Biomimetic materials in tissue engineering

185Citations
Citations of this article
446Readers
Mendeley users who have this article in their library.

Abstract

Biomaterial matrices are being developed that mimic the key characteristics of the extracellular matrix, including presenting adhesion sites and displaying growth factors in the context of a viscoelastic hydrogel. This review focuses on two classes of materials: those that are derived from naturally occurring molecules and those that recapitulate key motifs of biomolecules within biologically active synthetic materials. For biologically derived materials, methods are being sought to gain molecular-level control over biological characteristics and biomechanics. For synthetic, biomimetic materials, chemical schemes are being developed to enable in situ cross-linking and protease-dependent degradation and release of incorporated growth factors. These materials will open new doors to biosurgical therapeutics in tissue engineering and regenerative medicine. © 2010 Elsevier Ltd. All rights reserved.

Cite

CITATION STYLE

APA

Patterson, J., Martino, M. M., & Hubbell, J. A. (2010, January). Biomimetic materials in tissue engineering. Materials Today. https://doi.org/10.1016/S1369-7021(10)70013-4

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free