Actin stress fibers

583Citations
Citations of this article
877Readers
Mendeley users who have this article in their library.

Abstract

Animal cell movement is effected through a combination of protrusive and contractile events. Non-muscle cells contain stress fibres - bundles of actomyosin that are the major mediators of cell contraction and that can be compared to the highly organised actomyosin arrays of muscle cells. Recent studies have defined regulatory mechanisms that control stress fibre formation, placing the ROCK protein kinase at the centre of a complex signalling network controlling actomyosin contractility and stress fibre assembly. As we uncover the details of stress fibre construction, it is becoming clear that different categories of stress fibres exist. Some of these structures are less suited for cell motility and more suited to static contraction. In keeping with this, many specialised contractile cell types use stress fibres to remodel tissues and extracellular matrix.

Cite

CITATION STYLE

APA

Pellegrin, S., & Mellor, H. (2007). Actin stress fibers. Journal of Cell Science, 120(20), 3491–3499. https://doi.org/10.1242/jcs.018473

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free