Effect of fucoidan concentration from Sargassum sp. on skin lotion antioxidant activities

Abstract

Fucoidan is a polysaccharide with complex sulfate groups that are found in the cell walls of brown seaweed, one is Sargassum sp. This study aimed to determine the effect of addition fucoidan from Sargassum sp. on the antioxidant activity of skin lotion and to determine antioxidant activity of skin lotion with the addition of antioxidants after storage. The method used was experimental with completely randomized design (RAL) with four treatments and five replications. The treatments used are: P1 (fucoidan 1 X IC50), P2 (fucoidan 2 X IC50), P3 (fucoidan 3X IC50) and Control (Skin lotion with green tea extract commercial).The antioxidant activity testis done with DPPH method. The results showed that the IC50 value of fucoidan extract were 1407.667 ppm. In the result of adding fucoidan on skin lotion prode result IC50 values P1, P2, P3 and Control in a row was 1709, 816, 645 and 314 ppm. While the IC50 value of skin lotion 30th day in a row was 1723, 825, 699 and 323 ppm. Based on these results, the skin lotion with fucoidan has a weak antioxidant activity because it had IC50 values above 200 ppm, while storage for 30 days can increase the value of IC50.