Haplotype Analysis in Population-based Association Studies

Abstract

This paper describes how to use the command hapipf and introduces the command profhap written for Stata that analyzes population-based genetic data. For these studies, association can be linkage disequilibrium within a set of loci or al-lelic/haplotype association with disease status. Confidence intervals for odds ratios are calculated with or without adjustment for possible factors that are confounding the relationship. Additionally, this command allows the specification of many models of association that are not widely implemented.