Analysis and detection of DNA variation is important in any field of biology. Hence, numerous methods have been developed to analyze DNA. A simple yet effective way of analyzing DNA is by denaturant capillary electrophoresis (DCE). The method is in theory applicable to 95% of the human genome. The method involves three steps; fragment design, PCR amplification and allele separation. The allele separation can in principle be performed with any DNA capillary sequencing instrument. © 2008 Humana Press.
CITATION STYLE
Ekstrøm, P. O. (2008). Scanning for DNA variants by denaturant capillary electrophoresis. Methods in Molecular Biology, 439, 19–34. https://doi.org/10.1007/978-1-59745-188-8_2
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