THE RELEASE OF NEURAL TRANSMITTER SUBSTANCES

Abstract

Fig. 3 Inhibition of spontaneous action potentials in prolactin cells by catecholamines. Catecholamines (in recording solution) were applied to the cells by drug delivery pipette for periods indicated by bars under the records. a, Arrest of spontaneous discharge by noradrenaline (10-6 M NA). b, Similar effect, in a second cell, produced by dopamine (10-6 M DA). c, Slowing of spontaneous discharge, in a third cell, by a lower concentration of dopamine (10-8 M). Similar responses were obtained in 32 of 34 cells tested. affecting action potential activity in their target cells. Finally, in common with others 19-21 , we consider that the teleost pituitary, because of the segregation of cell types, offers unique advantages for the study of hypophysial function.