Current Developments in Diagnostic Biosensor Technology: Relevance to Therapeutic Intervention of Infectious and Inflammatory Diseases of Human

Abstract

The current scenario of various infectious and inflammatory diseases of humans is indeed alarming. Implication of appropriate therapeutic strategies in many diseases was found to be limited due to the lack/inefficiency of accurate diagnostic approach. In this context, biosensor technology has come out as an efficacious mean to meet the need. Several types of diagnostic biosensors viz. electrochemical, enzymatic, optical, aptamer-based, and immunosensors have been developed and modified throughout the last decade and few of them are currently in use. Since early detection is considered the key behind adopting accurate therapeutic strategies, use of biosensors is growing day by day. Such high demand in the market has come out as a promising prospect in different research institute and industries dedicated to human health care. Major limitations amongst the available biosensing devices are high cost, lower accuracy, and sensitivity. Therefore, the major challenge in modern biosensor research is the development of miniatured biosensors which will facilitate in situ diagnosis and treatment. More collaborative research among different scientific communities are particularly needed to overcome the aforesaid challenge. This chapter has been written with an intension to present a generalized overview on the relevance of the modern diagnostic biosensors in human healthcare especially for diagnosing human health problems with special emphases on infectious and infectious diseases.