Instability of repetitive DNA sequences within the genome is associated with a number of human diseases. The expansion of trinucleotide repeats is recognized as a major cause of neurological and neuromuscular diseases, and progress in understanding the mutations over the last 20 years has been substantial. Here we provide a brief summary of progress with an emphasis on technical advances at different stages.
CITATION STYLE
Budworth, H., & McMurray, C. T. (2013). Trinucleotide Repeat Protocols. Methods in Molecular Biology (Clifton, N.J.), 1010, 3–17. Retrieved from http://link.springer.com/10.1007/978-1-62703-411-1
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