Suppressive Effect of ERW on Lipid Peroxidation and Plasma Triglyceride Level

Abstract

Oxidative stress is produced as a result of imbalance due to excess formation of free radicals and decreased activity of antioxidant defense systems. All oxidative reac- tions are continuous sources of potentially cytotoxic reactive oxygen species (ROS), which play important roles in living systems both through their beneficial and detri- mental effects. Electrolyzed reduced water (ERW) generated nearby the cathode exhibited anti-oxidative properties, and suppressed tumor angiogenesis [1]. Here we investigated whether ERW prevents arteriosclerosis arisen from low-density lipoprotein (LDL) oxidation. We revealed that ERW inhibited LDL oxidation in vitro by macrophage cells. Furthermore, the effect of ERW on lipid peroxidation in tissues and lipid metabolism in plasma were examined in vivo.