Implantable optrode array for optogenetic modulation and electrical neural recording

6Citations
Citations of this article
9Readers
Mendeley users who have this article in their library.

Abstract

During the last decade, optogenetics has become an essential tool for neuroscience research due to its unrivaled feature of cell-type-specific neuromodulation. There have been several tech-nological advances in light delivery devices. Among them, the combination of optogenetics and electrophysiology provides an opportunity for facilitating optogenetic approaches. In this study, a novel design of an optrode array was proposed for realizing optical modulation and electrophys-iological recording. A 4 × 4 optrode array and five-channel recording electrodes were assembled as a disposable part, while a reusable part comprised an LED (light-emitting diode) source and a power line. After the characterization of the intensity of the light delivered at the fiber tips, in vivo animal experiment was performed with transgenic mice expressing channelrhodopsin, showing the effectiveness of optical activation and neural recording.

Cite

CITATION STYLE

APA

Jeon, S., Lee, Y., Ryu, D., Cho, Y. K., Lee, Y., Jun, S. B., & Ji, C. H. (2021). Implantable optrode array for optogenetic modulation and electrical neural recording. Micromachines, 12(6). https://doi.org/10.3390/mi12060725

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free