Granulomatous slack skin is an indolent T-cell lymphoma, considered to be a variant of mycosis fungoides. Clinically it is characterized by areas of redundant skin, wrinkled, inelastic, with variable erythema and infiltration besides a poikilodermic surface. A differential diagnosis unknown to most dermatologists is the giant cell tumor of soft tissue, which is an extremely rare low-grade sarcoma. The authors report a patient who had undergone extensive surgery because of a primary diagnosis of giant cell tumor of soft tissue, but which proved to be granulomatous slack skin after a second interventional procedure with confirmatory histopathology.
Adriano, A. R., Lima, T. S., Battistella, M., & Bagot, M. (2015). Granulomatous slack skin T-cell lymphoma: An important differential diagnosis with giant cell tumor of soft tissue. Anais Brasileiros de Dermatologia, 90(6), 892–895. https://doi.org/10.1590/abd1806-4841.20153807