A method to reconstruct activation wavefronts without isotropy assumptions using a level sets approach

Abstract

We report on an investigation into using a Level Sets based method to reconstruct activation wavefronts at each time instant from measured potentials on the body surface. The potential map on the epicardium is approximated by a two level image and the inverse problem is solved by evolving a boundary, starting from an initial region, such that a filtered residual error is minimized. The advantage of this method over standard activation-based solutions is that no isotropy assumptions are required. We discuss modifications of the Level Sets method used to improve accuracy, and show the promise of this method via simulation results using recorded canine epicardial data. © Springer-Verlag Berlin Heidelberg 2005.