Systemic gene delivery is useful for modeling and treatment of a body-wide disease. Recently, it has been shown that certain agents, when delivered systemically, can efficiently target the central nervous system. This technique has been used to model and treat rodent models of neurological disease with unprecedented success. Here, we describe intravenous delivery in neonate and adult mice. These techniques are easily learned and have minimal equipment requirements.
CITATION STYLE
Gombash, S. E., & Foust, K. D. (2016). Systemic gene therapy for targeting the CNS. In Methods in Molecular Biology (Vol. 1382, pp. 231–237). Humana Press Inc. https://doi.org/10.1007/978-1-4939-3271-9_16
Mendeley helps you to discover research relevant for your work.